Suicide attempts in major depressive episode: evidence from the BRIDGE-II-Mix study

Résumé

textbfOBJECTIVES: The Bipolar Disorders: Improving Diagnosis, Guidance, and Education (BRIDGE-II-Mix) study aimed to estimate the frequency of mixed states in patients with a major depressive episode (MDE) according to different definitions and to compare their clinical validity, looking into specific features such as suicidality. textbfMETHODS: A total of 2,811 subjects were enrolled in this multicenter cross-sectional study. Psychiatric symptoms, and sociodemographic and clinical variables were collected. The analysis compared the characteristics of patients with MDE with (MDE-SA group) and without (MDE-NSA) a history of suicide attempts. textbfRESULTS: The history of suicide attempts was registered in 628 patients (22.34%). In the MDE-SA group, women (72.5%